Perfilado de sección




    • Three major IGFBPs are detected in serum/plasma of salmonids. They are believed to inhibit or/and promote action of IGF-I.






    • Functional analysis using recombinant IGFBP-1a and -1b revealed that IGFBP-1a inhibited the action of IGF-I on GH release from the pituitary gland.